Our liver is the major organ of digestion and detoxification, transforming hormones, chemicals, drugs, alcohol and toxins that we get from our environment into a form that we can excrete. Inadequate liver function and detoxification may be associated with fatigue, weakness, bloatedness, indigestion, constipation, headaches, elevated cholesterol, food intolerance or chemical insensitivity.

Each capsule of Healtheries Liver Aid contains 12,500mg of Milk Thistle that has been standardised to provide 150mg of the active constituent Silymarin which scientific research has shown to both protect and stimulate the regeneration of liver cells.

Recommendations For Use:

• Chronic fatigue especially when associated with digestive upset
  
• Abdominal bloating
  
• Indigestion
  
• Nausea especially after eating fatty foods
  
• Constipation
  
• Allergies, especially when first occur as an adult
  
• Food intolerance
  
• Chemical sensitivity
  
• Overweight
  
• Elevated blood fats and cholesterol
  
• Skin complaints
  
• Leaky gut syndrome
  
• Heavy alcohol intake
  
• Sugar cravings
  
• Wake in the morning with bad breath and coated tongue
  
• Headaches associated with digestive upset or food intolerance
  
• Glandular fever to speed recovery from
  
• Hepatitis to speed recovery from
  
• Pre-menstrual syndrome
  
• Menopausal symptoms

Contra-Indications:

• None

Dose:

• Adults: Take 1-2 capsules a daily or as directed by your health practitioner .
  
• Take before meals.

Contains No:

• GLUTEN, MILK DERIVATIVES, YEAST, SUGAR, CORN, STARCH, COLOUR, FLAVOUR OR PRESERVATIVES

Pack Information:

• Available in a bottle of 30 capsules.

Ingredients:

Ingredient Information:

Milk Thistle (Silybum marianum - sometimes referred to as St Mary’s Thistle)

• Part of plant used: seeds, fruit leaves
  
• Chemical Composition : Silybum marianum contains silymarin, a mixture of flavanolignans, consisting chiefly of silybin, silydianin and silychristine. The concentration of silymarin is highest in the fruit but is also found in the seeds and leaves. The most biologically active component of silymarin is silibin.
  
• Silymarin is one of the most potent liver protecting substances known. Its action is one of inhibiting free radical damage and is many times more potent in antioxidant activity than Vitamin E.
  
• Silymarin not only prevents the depletion of glutathione induced by alcohol and other liver toxins but actually increases the level of glutathione within the liver.
  
• Silymarin inhibits the liver’s production of both inflammatory prostaglandins[1] and leukotrienes[2]. It does this by inhibiting the lipoxygenase enzyme[2] and the decomposition of membrane lipids and prostaglandin formation.
  
• The protective effect of Silybum marianum has been demonstrated in a number of experimental and clinical studies.[1-14]
  
• Milk Thistle also stimulates protein synthesis within the liver. This results in an increase in the production of new liver cells replacing damaged old ones[9,10] but does not have a stimulatory effect on malignant liver tissue[9].
  
• Silymarin is particularly effective in protecting against alcohol and chemical-induced liver damage, and may have value in viral hepatitis. Silymarin has also been reported to be of value in psoriasis[15] and may be due to improved liver function or inhibition of leukotrienes and cyclic AMP-phosphodiesterase.
  
• The liver is closely associated with psoriasis. Psoriasis has been shown to be linked with high levels of circulating endotoxins such as those found in the cell walls of gut bacteria. If the liver is overwhelmed by an increased amount of endotoxin or chemical toxin or the liver’s ability to filter and detoxify is decreased psoriasis gets much worse.

Dandelion (Taraxacum officinale)

• Part Used : Root
  
• Is a digestive and hepatic tonic, has diuretic and laxative properties.
  
• Induces the flow of bile from the liver.
  
• Traditionally used in gallstone and biliary problems, jaundice, dyspepsia associated with constipation.

Lecithin

• Makes up phospholipids, a constituent of cell membranes.
  
• Is a complex mixture of fatty acids, including the essential fatty acids (linoleic 55%, linolenic 7%) phosphorus and two B group vitamins, choline (8.2%) and inositol (2.2%).
  
• Is a biological emulsifier increasing the solubility of fat and cholesterol, thereby decreasing their ability to clog arteries (atherosclerosis).
  
• Aids in the removal of cholesterol from tissue deposits and inhibits platelet aggregation.[16]
  
• Low lecithin concentration in the bile may be a causative factor in many gallstones.[17] Studies have shown that 100mg of lecithin three times daily will increase the concentration of lecithin in bile, larger doses (up to 10 grams) produce even greater increases.[18, 19]
  
• Is present in all cells and organs of the human body and is essential for : the structure of nerve tissue,for a healthy nervous system; proper functioning of glands including sex glands; makes up 30% of the dry weight of the brain; makes up 73% of the total liver fat

Taurine

• Helps maintain the correct composition of bile and the solubility of cholesterol.

References:

[1]Fiebrich F and Koch H: Silymarin, an inhibitor of prostaglandin synthetase. Experentia 35:150-2, 1979.
[2] Fiebrich F and Koch H: Silymarin, an inhibitor of lipoxygenase. Experentia 35:148-50, 1979.
[3] Wagner H: Antihepatotoxic flavonoids. In: Plant Flavonoids in Biology and Medicine: Biochemical, Pharmacological, and Structure-Activity relationships. Edited by Cody V, Middleton E and Harbourne JB. Alan R Liss, Inc, New York, NY, 1986. pp545-58.
[4] Adzet T: Polyphenolic compounds with biological and pharmacological activity. Herbs Spices Medicinal Plants 1:167-84, 1986.
[5] Hikino H, Kiso Y, Wagner H, and Fiebig: Antihepatotoxic actions of flavanolignans from Silybum marianum fruits. Planta Medica 50:248-50, 1984.
[6] Vogel G, Tuchweber B, Trost W, and Mengs U: Protection against Amanita phalloides intoxication in beagles. Toxicol Appl Pharm 73:355-62, 1984.
[7] Vogel G, Trost W, Braatz R, et al: Studies on pharmacodynamics, site and mechanism of action of silymarin, the antihepatotoxic principle from Silybum marianum (L.) Gaert. Arzneim-Forsch 25:179-85, 1975.
[8] Grieve M: A Modern Herbal, volume 1. Dover Publications, New York, NY, 1971. pp385-6.
[9] Sonnenbichler J, Goldberg M, Hane L, et al: Stimulatory effect of silibinin on the DNA synthesis in partially hepatectomised rat livers: non-response in hepatoma and other malignant cell lines. Biochem Pharm 35:538-41, 1986.
[10] Sonnenbichler J and Zetl I: Biochemical effects of the flavanolignane silibinin on RNA, Protein and DNA synthesis in rat livers. In: Plant Flavonoids in Biology and Medicine: Biochemical, Pharmacological, and Structure-Activity relationships. Edited by Cody V, Middleton E and Harbourne JB. Alan R Liss, Inc, New York, NY, 1986. pp319-31.
[11] Salmi HA and Sarna S: Effect of silymarin on chemical, functional and morphological alteration of the liver. A double-blind controlled study. Scand J Gastroenterol 17:417-21, 1982.
[12] Scheiber V and Wohlzogen FX: Analysis of a certain type of 2 X 3 tables, exemplified by biopsy findings in a controlled clinical trial. Int J Clin Pharm 16:533-5, 1978.
[13] Boari C, Montanari M, Galleti GP, et al: Occupational toxic liver diseases. Therapeutic effects of silymarin. Min Med 72:2679-88.
[14] Cavalieri S: A controlled clinical trial of Legalon in 40 patients. Gazz Med Ital 133:628-35.
[15] Herbal Medicine Rudolf Fritz Weiss, p. 88.
[16] Brook JG, Linn S and Aviram J. ‘Dietary soya lecithin decreases plasma triglyceride levels and inhibits collagen and ADP induced platelet aggregation’. Biochem. Med. Metabol., 1986, 35 pp 31-39.
[17] Encyclopedia of Natural Medicine – Pizzorno & Murray.
[18] Weisberg HF ‘Pathogenesis of gallstones’. Annals. Clin. Lab. Sci. 1984, 14 pp 243-51.
[19] Trowell H, Burkitt D and Heaton K. ‘Dietary fibre, fibre depleted foods and disease’. Academic Press NY 1985, pp 289-304