Taking a diet rich in omega-3 fatty acids is beneficial to patients with arthritis such as rheumatoid arthritis and osteoarthritis as they slow down the development of the joint disease. Fish oil supplementation is, therefore, a valuable support to the conventional drug treatment of rheumatoid arthritis. Studies have shown that patients taking fish oil supplements for rheumatoid arthritis require fewer pain medications. In a recent study, a significant reduction in the patient-reported intensity of joint, duration of morning stiffness, number of painful and/or tender joints including consumption of painkillers (NSAIDs) has been reported with omega-3 fatty acids.
Asthma has been defined as a chronic inflammatory disease of the airways. Due to their anti-inflammatory properties, research suggests that omega-3 fatty acid supplements may decrease inflammation and improve lung function in patients with asthma. One clinical trial of omega-3 fatty acids supplementation in children with asthma found that those who took fish oil supplements rich in EPA and DHA for 10 months had improvement in their symptoms compared to children who took a placebo pill.
An Australian study showed that eating oily fish more than once per week protects children against asthma. Omega-3 fatty acids are also useful in reducing exercise-induced asthma.
Earlier studies have reported a lower prevalence of impaired glucose tolerance and type 2 diabetes in populations who took large amounts of omega-3 fatty acids found mainly in fish. People with type 2 diabetes are known to be at increased risk of heart attack or stroke. Diabetics typically have high levels of fats (TGs) in the blood, low levels of good cholesterol (HDL cholesterol) and abnormal LDL (low-density lipoprotein) composition. Omega-3 fatty acids from fish lower TGs, reduce abnormal heart rhythms, lower blood pressure and improve blood clotting regulation. Clinical studies have shown that consumption of omega-3 fatty acids has cardioprotective effects in persons with type 2 diabetes without adverse effects on glucose control and insulin activity.
Fish oil may be useful in treating dyslipidemia in diabetes. Fish oil supplementation improved plasma VLDL cholesterol, VLDL TGs, and total TGs while having a transient deterioration in LDL cholesterol in patients with noninsulin-dependent diabetes (NIDDM). Furthermore, fish oil supplementation had no significant deleterious effect on glycemic control. Plasma LDL cholesterol was temporarily increased in the fish oil group at 6 weeks, but the effect was no longer present at 12 weeks. A diet rich in fish and other sources of omega-3 fatty acids reduces the chances of children with a family history of diabetes to develop the disease. In type 2 diabetic patients, supplementation with 1.7 g/day to all patients for a further six months produced no deterioration of glucose control after one year of treatment. Preliminary evidence suggests increased consumption of n-3 PUFAs with reduced intake of saturated fat may reduce the risk of conversion from impaired glucose tolerance to type 2 diabetes in overweight persons.
The term â€˜inflammatory bowel disease (IBD) refers to two chronic diseases that cause inflammation of the bowels or intestines: ulcerative colitis and Crohnâ€™s disease. Omega-3 fatty acids have the most potent immunomodulatory activities, and among the omega-3 PUFA, those from fish oil (EPA and DHA) are more biologically potent than ALA. Hence, these fatty acids may inhibit an increase of proinflammatory markers. When added to standard medication, such as sulfasalazine, omega-3 fatty acids may reduce symptoms of Crohnâ€™s disease and ulcerative colitis. In children with Crohnâ€™s disease, omega-3 FAs (EPA and DHA) together with mesalazine treatment (5-ASA) effectively maintained disease remission. Children who were given omega-3 fatty acids also suffered fewer relapses.
Omega-3 fatty acids relieve depressive symptoms related to menopause. A study published in the American Journal of Clinical Nutrition presented the first evidence that EPA supplementation is effective for treating common menopause-related mental health problems and improves depressive symptoms. Middle-aged women were grouped into two and were randomly administered either daily supplements of omega-3 fatty acids (EPA+DHA) or placebo (sunflower oil) for eight weeks. At the beginning of the study, all of the participants were classified as having mild-to-moderate depression and about one-quarter of them had experienced major depressive episode. Omega-3 fatty acids significantly improved the condition of women suffering symptoms of psychological distress and mild depression at the end of the study. The researchers also noted that the difference in the observed results between the two groups was remarkable especially keeping in view that omega-3 fatty acids have very few side effects and are beneficial to heart health.
Supplementation with EPA omega-3 fatty acids reduced frequency of hot flashes (HF) and also improved the HF score relative to placebo. At the start of the study, the number of daily hot flashes experienced by the women was 2.8 in a day. There was a significant decrease in the number of daily hot flashes over the 8-week study, with a greater decrease observed among women consuming EPA. The number of hot flashes declined by 1.58/day in the EPA group versus 0.5/day decrease in the control group. The quality-of-life also improved in both groups.59
Menstrual pain or dysmenorrhea is the most common gynecologic complaint and the leading cause of short-term absenteeism among adolescent schoolgirls. In a clinical study of nearly 200 Danish women aged between 20 and 45 years, a strong association was observed between increased menstrual pain and a low intake of omega-3 fatty acids from fish.
In a study, adolescents suffered less menstrual pain while taking fish oil supplementation; the amount of painkillers taken during the menstrual periods also declined by more than 50%.
The brain is one of the organs in the body with the highest level of lipids (fats). Omega-3 fatty acids are important components of nerve cell membranes. DHA, in particular, is involved in various nerve cell processes. Omega-3 fatty acids from fatty fish in the human diet may be effective in the prevention of stress and other disease conditions including depression, and dementia.
In a review of evidence of omega-3 fatty acid in depression, four of seven trials showed significant improvement of depression with at least 1 g/day of EPA. Results from a trial have also shown therapeutic benefits with omega-3 fatty acids in depression during pregnancy. In a Finnish study, the risk of depression and suicidality was much lower in those who frequently ate fish.
Scientists in Taiwan compared omega-3 supplementation (10 capsules per day, each containing EPA 440 mg and DHA 220 mg) with usual treatment in patients diagnosed with a major depressive disorder for a duration of eight weeks and concluded that omega-3 PUFAs could improve the short-term course of illness. Patients on omega-3 supplementation experienced a significantly greater decrease in the Hamilton Depression Scale score than did those in the control group. In another clinical study of 30 people with bipolar disorder, omega-3 fatty acids (EPA and DHA 9.6 g/day) in addition to usual treatment for four months could maintain mood stability; also, patients experienced fewer mood swings and recurrence of either depression or mania than those who received a controlled drug.
Preliminary clinical evidence suggests that people with schizophrenia experience an improvement in symptoms when given omega-3 fatty acids. Omega-3 fatty acids reduce the antipsychotic drug requirement in first episode patients with schizophrenia and may be an effective adjunct to antipsychotics. But, a recent study observed no additional benefits of EPA supplements than placebo in improving symptoms of schizophrenia.
Children with attention-deficit/hyperactivity disorder (ADHD) may have low levels of EFAs including EPA and DHA. In a clinical study of about 100 boys, learning and behavioral problems (such as temper tantrums and sleep disturbances) were more common in boys with lower omega-3 fatty acid levels than those with normal omega-3 fatty acid levels.
A child diagnosed with autism who received 540 mg of the omega-3 fatty acid daily in the form of EPA for four weeks experienced a complete end to his previous anxiety about everyday events as reported by his parents and clinician. His overall quality-of-life was also improved. In another trial, most parents of 18 children with autism who had been given fish oil supplements for six months described improvements in overall health, cognition, sleep patterns, social interactions and eye contact. A recent trial reported reduced hyperactivity and reduced stereotypy (repeated movements like hand-flapping) in children who received 1.5 g of fish oil per day, as compared to children who received placebo.
Omega-3 fatty acids have also been researched in eating disorders such as anorexia nervosa. In a pilot study of EPA supplementation in the treatment of anorexia nervosa in seven young patients, three recovered and four improved.
Omega-3 fatty acid supplementation may have an inverse relationship with the risk of dementia and cognitive decline. People who have diets rich in fish would have a significantly lower risk of dementia and Alzheimerâ€™s disease. Omega-3 fatty acid supplements may slow cognitive decline in some patients with very mild Alzheimerâ€™s disease, though they do not appear to affect those with more advanced cases. A study by researchers at Tufts University in Boston found that people with the highest blood levels of DHA had a 47% lower risk of developing dementia and a 39% lower risk of developing Alzheimerâ€™s. The study analyzed the blood of 899 men and women with an average age of 76. All participants were free of dementia at the beginning of the study, and underwent neuropsychological testing after giving their initial blood sample. In patients with mild cognitive impairment, a significant improvement in the cognitive portion of the Alzheimerâ€™s Disease Assessment Scale (ADAS-cog) was noted.
Osteoporosis is a disease in which the bones become weak and are more prone to fractures. It is also called as the â€˜silent diseaseâ€™ as bone is lost with no signs. Such fractures are common in the hip, spine and wrist. Osteoporosis can strike at any age but is most common in older women.
An expanding body of evidence indicates that omega-3 fatty acids are also beneficial to bone health. They may help increase calcium levels in the body, deposit calcium in the bones and enhance bone strength. Studies have also indicated that individuals who lack essential fatty acids (particularly EPA and gamma-linolenic acid [GLA], an omega-6 fatty acid) are more prone to develop loss of bone than those with adequate levels of these EFAs.
In a study of elderly women with osteoporosis, those who were given EPA and GLA supplements had considerably less bone loss over a period of three years than those who were given a placebo. Many of these women also experienced an increase in bone density during this time. In young healthy men, an 8-year study showed that omega-3 fatty acids, especially DHA was positively associated with an increase in bone mineral and, hence, with peak bone mineral density (BMD). The study by Weiss et al has observed a negative association between a higher omega-6 to omega-3 fatty acids ratio and bone density at the hip in both sexes.
Omega-3 fatty acids may facilitate weight loss. They do so by
By helping regulate blood sugar levels in the body, a diet rich in omega-3 fatty acids can help keep hunger in check, thus aiding weight loss. In overweight and obese volunteers, there were fewer hunger sensations in the omega-3 fatty acid group immediately after the test dinner and after 120 minutes. Combining fish-oil supplements with regular aerobic exercise improves body composition by reducing body fat. In a study, 66% of young European overweight adults consumed less than the generally the recommended intake of fish.
Mrs. Chitra Narain
Retired Media Professional, Jangpura, New Delhi
In the 1980s I started suffering from arthritis. I went to doctor he advised me knee replacement. I was not ready for it. One day I saw an advertisement in the newspaper regarding Seatone. I started taking two capsules every day. Use of Seatone provided me miraculous results.
Mrs. Renuka Gupta
Retired MNC Professional, Lajpat Nagar, New Delhi
I am suffering from arthritis from 30 years. I used to suffer severe knee pain. I consulted many doctors but I was not able to get treated. One day I came to know about Seatone from a friend. I started using it in 2003. I felt a great relief and comfort with its continuous use.
Mrs. Abha Saxena
Two years back I felt pain in my foot. I went to the doctor, he diagnosed degeneration of knee bone through X-ray. He advised me knee replacement and some medicines. I was not much benefited with the medicines. One day I came to know about Seatone at my friend′s place. I used Seatone regularly for two months. After one year again I suffered from the same pain. I again started Seatone capsules and now I am completely fine.
Mr. Rajeev Sharma
Sr. Auditor, Government Service, Palwal, Haryana
My mother was suffering from arthritis 5-6 years back. She was even unable to walk. But she was not ready to visit doctors. Therefore I started researching about the treatments of arthritis. I came to know about Seatone. My mother used Seatone for 8-9 months. Now she is quite fine.
Col. Retd. Anthony Abraham
Indian Army, Vasant Kunj, New Delhi, Indian Army, Vasant Kunj, New Delhi
Mrs. Nivedita Kamal
Retired Banker, Dwarka, New Delhi, Retired Banker, Dwarka, New Delhi
Dr. Krishan Bir Chaudhary
President of Bharatiya Krishak Samaj, President of Bharatiya Krishak Samaj
Mr. Ajay Gupta
Businessman, Faridabad, Haryana, Businessman, Faridabad, Haryana
Healtheries Seatone, a 100% extract of the New Zealand Green Lipped Mussel (GLM), contains anti-inflammatory agents, immune modulators and many essential building blocks, all naturally occurring substantial therapeutic agents known to maintain joint mobility & well being.
Seatone Vs Other GLME Brands
For the formation of GLME extracts the processing conditions vary. The production of Seatone meets the internationally accredited standards. Its preservation starts right after its harvesting. Its quality of raw material, processing methods and product quality is tested by the testing agencies.
What is Squalene?
Squalene is an unsaturated isoprenoid that occurs naturally in several seeds and also found in the bodies of animals. Among vegetable oils, olive oil is the rich source of squalene. It is also found in human body.
How long Seatone should be taken to see the desired results?
On the onset of arthritis, GLME use provides immediate relief. In grade-2 of arthritis it will take much more time and in grade-3 of arthritis, you need to be patient because regeneration is a slow process. The reduction of inflammation and synthesis of the membrane will be delayed in this grade- 3.
What are the Risk Factors for Arthritis?
There are several factors that increase the risk of arthritis. The main factor is the gender of a person. Women are more prone to develop arthritis than men. The other factors are your lifestyle, age and genetics that contribute to increased the risk of arthritis.
Arthiritis in Female
The number of women suffering from arthritis is more than the number of men suffering from arthritis. There are a number of factors that contribute to the development of arthritis in women, such as the number of births given by a woman. Arthritis can affect any section of society.
What is Osteoarthritis & its symptoms, diagnosis, prevention and treatment alternative available?
Seatone Vs Other GLME Brands
For the formation of GLME extracts, the processing conditions vary. The production of Seatone meets the internationally accredited standards. Its preservation starts right after its harvesting. Its quality of raw material, processing methods and product quality is tested by the testing agencies.
Obesity and Arthritis
Obese people are more susceptible to develop arthritis then the healthy people because their legs are not able to support the excessive weight of their upper body. Obese people are more likely to develop knee problems. The only way for the obese people to manage arthritis is to reduce their weight in a scientific way.
What are the risk factors affecting Women and Osteoarthritis?
There are a number of factors responsible for the higher risk of developing osteoarthritis in women. The major one is diet. During pregnancy, the calcium is extracted by the fetus and after the birth of baby milk production extracts a lot of calcium, which makes the bones of women weak. Therefore, the chance of developing arthritis increases.
Is GLME Safe For Diabetic Patients Suffering From Arthritis?
GLME is safe for diabetic patients suffering from arthritis as it has a marine origin. The marine foods are recommended for the patients with diabetes. There is no harm linked with GLME for the diabetic patients.
Green Lipped Mussel in Rheumatoid Arthritis Pain Management
GLME of New Zealand waters is an excellent remedy for controlling rheumatoid arthritis. GLME contains various components that act as a building block for the collagen. They rebuilt the damaged tissues and with their continuous use, cartilage can come back to their normal conditions.